Functional Ultrasound Scanner

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        "description": "This contract award notice refers to the purchase of a functional ultrasound (fUS) scanner (not to be confused with FUS which is focussed ultrasound \u2013 which is used for ultrasound therapy applications such as ablation).\nEssential Scanner Features\nNon-invasive brain imaging: Imaging of brain blood flow dynamics in the mouse brain without the need to create an acoustic window\nHigh spatial resolution: Ability to achieve real-time spatial resolution better than 100 microns sufficient for visualising the mouse brain\nHigh temporal resolution: Ability to achieve temporal resolution better than 100 ms to enable dynamic imaging of brain blood flow\nAtlas registration: In-built Allen brain atlas so that the acquired brain images can be registered\nFunctional connectivity analysis: In-built interactive software to build connectivity matrices, seed maps, and perform region-based analyses.\nUltrasound localisation microscopy: Capability for super-resolution imaging and visualisation of the microvascular tree in the brain or other soft tissue organs, including associated analysis software.\n3D imaging support: Ability to perform volumetric imaging and reconstruction of brain regions.\nBlood flow velocity analysis: Software to support calculation of the velocity of blood moving within the micro- vasculature of the brain or other soft tissue organs\nPortability and motorised scanning: Portable/moveable system with motorised scanning table and associated hardware to support ultrasound scanning of fixed-head or fixed-organ animals.\nOffline analysis: Full capability for offline data analysis, including export to standard analysis platforms (e.g. MATLAB, Python).\nAwake and anaesthetised imaging: System adaptable for both anaesthetised and awake mouse imaging, including head-fixation and behavioural setups.\nPhysiological synchronisation: Compatibility with physiological monitoring systems (e.g. ECG, respiration) and synchronisation with external equipment such as stimulation, electrophysiology, or behavioural tracking systems.\nUpgrade and expandability: Modular design to support future hardware or software upgrades (e.g. dual-probe imaging, extended field-of-view).\nTraining and technical support: Comprehensive technical support, including on-site installation, user training, software updates, and a warranty/maintenance plan.",
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    "title": "Functional Ultrasound Scanner"
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